0001144204-11-072394 Sample Contracts

CONTROLLED EQUITY OFFERING AGREEMENT
Controlled Equity Offering Agreement • December 30th, 2011 • Apricus Biosciences, Inc. • Pharmaceutical preparations • New York

Apricus Biosciences, Inc., a corporation organized under the laws of Nevada (the “Company”), confirms its agreement (this “Agreement”) with Ascendiant Capital Markets, LLC (the “Manager”) as follows:

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