0001144204-12-011073 Sample Contracts

AMENDMENT TO AMENDED AND RESTATED MANUFACTURING AND SUPPLY AGREEMENT
Manufacturing Agreement • February 27th, 2012 • Biomimetic Therapeutics, Inc. • Surgical & medical instruments & apparatus

This Amendment to the Amended and Restated Manufacturing and Supply Agreement (the “Amendment”) is entered into as of the 2nd day of February, 2012 and is deemed to have come into effect on 1 January 2012 (the “Effective Date”), by and among Novartis Vaccines and Diagnostics, Inc., with its principal place of business located at 350 Massachusetts Avenue, Cambridge, MA 02139 USA (hereinafter “Novartis”), and BioMimetic Therapeutics, Inc a Delaware corporation, with its principal place of business located at 389 Nichol Mill Lane, Franklin, Tennessee 37067 (hereinafter “BMTI”).

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