0001144204-12-019159 Sample Contracts

AMENDED AND RESTATED LICENSE AGREEMENT BETWEEN THE JOHNS HOPKINS UNIVERSITY ROSETTA GENOMICS LTD JHU Ref: A20281
License Agreement • April 2nd, 2012 • Rosetta Genomics Ltd. • Pharmaceutical preparations • Maryland

THIS LICENSE AGREEMENT (the “Agreement”) is entered into by and between THE JOHNS HOPKINS UNIVERSITY, a Maryland corporation having an address at 3400 N. Charles Street, Baltimore, Maryland, 21218-2695 (“JHU”) and Rosetta Genomics Ltd., an Israeli corporation having an address at 10 Plaut St. Rehovot (“Company”), with respect to the following:

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SECURITY INTEREST AGREEMENT
Security Interest Agreement • April 2nd, 2012 • Rosetta Genomics Ltd. • Pharmaceutical preparations • New York

Reference is made to (i) that certain Secured Loan Agreement, dated as of January 26, 2012 (the “Loan Agreement”), by and among the Lenders named therein (each, a “Secured Party” and collectively, the “Secured Parties”), and Rosetta Genomics Ltd., incorporated under the laws of the State of Israel, with headquarters (and registered office in accordance with Israeli Companies Law, 1999) located at 10 Plaut Street, Science Park, Rehovot 76706, Israel (the “Company”, or the “Debtor”), and (ii) the Transaction Agreements, including, without limitation, the Debentures. Capitalized terms not otherwise defined herein shall have the meanings ascribed to them in the relevant Transaction Agreements.

SECURED LOAN AGREEMENT
Secured Loan Agreement • April 2nd, 2012 • Rosetta Genomics Ltd. • Pharmaceutical preparations • New York

THIS SECURED LOAN AGREEMENT, dated as of January 26, 2012, is entered into by and between Rosetta Genomics Ltd., a corporation incorporated under the laws of the State of Israel, with headquarters located at 10 Plaut Street, Science Park, Rehovot 76706, Israel (the “Company”), and each individual or entity named on an executed counterpart of the signature page hereto (each such signatory is referred to as a “Lender”) (each agreement with a Lender being deemed a separate and independent agreement between the Company and such Lender, except that each Lender acknowledges and consents to the rights granted to each other Lender [each, an “Other Lender”] under such agreement and the Transaction Agreements, as defined below, referred to therein).

LICENSE AGREEMENT
License Agreement • April 2nd, 2012 • Rosetta Genomics Ltd. • Pharmaceutical preparations • New York

This License Agreement (“Agreement”) is made effective as of October 10, 2011 (“Effective Date”) by and between Rosetta Genomics Ltd., a corporation organized under the laws of Israel, having its principal place of business at 10 Plaut St., Rehovot, Israel, 76706 (“Rosetta”), and Avatao Biotech, a Chinese corporation with its principal place of business at 209 Chengfeng Rd. Yushanzhen, Kunshan, China 215300 (“Avatao”), Rosetta and Avatao are each hereafter referred to individually as a “Party” and together as the “Parties”.

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