0001144204-13-062306 Sample Contracts

6,666,667 Shares Chelsea Therapeutics International, Ltd. Common Stock ($0.0001 Par Value) UNDERWRITING AGREEMENT
Underwriting Agreement • November 15th, 2013 • Chelsea Therapeutics International, Ltd. • Biological products, (no disgnostic substances) • New York

Chelsea Therapeutics International, Ltd., a Delaware corporation (the “Company”), proposes to sell to the several underwriters (the “Underwriters”) named in Schedule I hereto for whom you are acting as representative (the “Representative” or “you”) an aggregate of 6,666,667 shares (the “Firm Shares”) of the Company’s common stock, $0.0001 par value (the “Common Stock”). The respective amounts of the Firm Shares to be so purchased by the several Underwriters are set forth opposite their names in Schedule I hereto. The Company also proposes to sell at the Underwriters’ option an aggregate of up to 1,000,000 additional shares of the Company’s Common Stock (the “Option Shares”) as set forth below. The Firm Shares and the Option Shares (to the extent the aforementioned option is exercised) are herein collectively called the “Shares.”

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