0001144204-13-069502 Sample Contracts

LICENSE AGREEMENT
License Agreement • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories • Arkansas

THIS LICENSE AGREEMENT (this “AGREEMENT”) is made by and between the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences, a public institution of higher education having principal offices at 2404 North University Avenue, Little Rock, Arkansas 72207, United States of America (hereinafter “UNIVERSITY”), and Myeloma Health LLC, a Delaware limited liability company having a principal office at 667 Madison Avenue, 14th Floor, New York, New York 10065 (hereinafter “LICENSEE”), as of the EFFECTIVE DATE (as later defined herein).

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AMENDMENT #2 to the LICENSE AGREEMENT
License Agreement • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories

THIS AMENDMENT (“Amendment”) is made by and between the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences, a public institution of higher education having principal offices at 2404 North University Avenue, Little Rock, Arkansas 72207, United States of America (hereinafter “University”), and Myeloma Health LLC, a Delaware limited liability company having a principal office at 667 Madison Avenue, 14th Floor, New York, New York 10065 (hereinafter “Licensee”).

FIRST AMENDMENT TO LICENSE AGREEMENT
License Agreement • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories

THIS FIRST AMENDMENT (this “AMENDMENT”), made as of September 1, 2010 amends the certain License Agreement, effective as of April 1, 2010 (the “AGREEMENT”), entered into by and between the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences, a public institution of higher education having principal offices at 2404 North University Avenue, Little Rock, Arkansas 72207, United States of America (hereinafter “UNIVERSITY”), and Myeloma Health LLC, a Delaware limited liability company having a principal office at 667 Madison Avenue, 14th Floor, New York, New York 10065 (hereinafter “LICENSEE”), and shall be effective as of the EFFECTIVE DATE (as such term is defined in the AGREEMENT).

AMENDMENT #4 to the LICENSE AGREEMENT
License Agreement • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories

This Amendment (“Amendment”) is made by and between the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences, a public institution of higher education having principal offices at 2404 North University Avenue, Little Rock, Arkansas 72207 (hereinafter “University”), and Myeloma Health LLC, a Delaware limited liability company having a principal office at 667 Madison Avenue, 14th Floor, New York, New York 10065 (hereinafter “Licensee”).

ASSIGNMENT OF MEMBERSHIP INTERESTS
Assignment of Membership Interests • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories • Delaware

THIS ASSIGNMENT OF MEMBERSHIP INTERESTS (this “Agreement”) dated as of January 1, 2011, made by and among LEBOW ALPHA LLLP, a Delaware limited liability limited partnership (“LeBow Alpha”), and SIGNAL GENETICS, LLC, a Delaware limited liability company (“Signal”).

AMENDMENT #3 to the LICENSE AGREEMENT
License Agreement • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories

This Amendment No. 3 (“Amendment No. 3”) is made by and between the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences, a public institution of higher education having principal offices at 2404 North University Avenue, Little Rock, Arkansas 72207 (hereinafter “University”), and Myeloma Health LLC, a Delaware limited liability company having a principal office at 667 Madison Avenue, 14th Floor, New York, New York 10065 (hereinafter “Licensee”).

FIRST AMENDMENT TO AMENDED AND RESTATED LIMITED LIABILITY COMPANY AGREEMENT OF SIGNAL GENETICS LLC
Limited Liability Company Agreement • December 30th, 2013 • Signal Genetics LLC • Services-medical laboratories • Delaware
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