0001144204-14-060628 Sample Contracts

SUBSCRIPTION AGREEMENT
Subscription Agreement • October 10th, 2014 • Synthetic Biologics, Inc. • Pharmaceutical preparations

This Subscription Agreement (this “Subscription”) is dated October 10, 2014, by and between the investor identified on the signature page hereto (the “Investor”) and Synthetic Biologics, Inc., a company incorporated and registered in the State of Nevada (the “Company”), whereby the parties agree as follows:

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SYNTHETIC BIOLOGICS, INC. 14,059,616 Shares of Common Stock Warrants to Purchase 7,029,808 Shares Placement Agency Agreement
Placement Agency Agreement • October 10th, 2014 • Synthetic Biologics, Inc. • Pharmaceutical preparations • New York

Synthetic Biologics, Inc., a Nevada corporation (the “Company”), proposes, subject to the terms and conditions herein, to issue and sell an aggregate of up to 14,059,616 (the “Shares”), of common stock $0.001 par value per share (the “Common Stock”) and warrants (in the form attached hereto as Exhibit B, the “Warrants”) to purchase 7,029,808 shares of Common Stock in Units (each a “Unit”) consisting of (i) one share of Common Stock and (ii) one Warrant to purchase 0.50 of a share of Common Stock to certain investors (each an “Investor” and collectively the “Investors”), in an offering under its registration statement on Form S-3 (Registration No. 333-189794). The number of shares of Common Stock issuable upon exercise of the Warrants is hereinafter referred to as the “Warrant Shares.” The Warrant Shares, together with the Shares and the Warrants, are referred to herein as the “Securities.” The Shares and Warrants are more fully described in the Disclosure Package (as defined in Section

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