0001144204-17-032365 Sample Contracts

SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • June 13th, 2017 • Northwest Biotherapeutics Inc • Pharmaceutical preparations • New York

THIS SECOND SUPPLEMENTAL INDENTURE (this “Second Supplemental Indenture”), dated and effective as of June 7, 2017, between Northwest Biotherapeutics, Inc. (the “Company”) and The Bank of New York Mellon, a New York banking corporation, as trustee (the “Trustee”). Capitalized terms used herein and not otherwise defined have the meaning ascribed to such terms in the Indenture (as defined below).

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