0001144204-18-021343 Sample Contracts

AMENDMENT NUMBER THREE TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • April 19th, 2018 • Rosetta Genomics Ltd. • Pharmaceutical preparations

This AMENDMENT NUMBER THREE TO LOAN AND SECURITY AGREEMENT (this “Amendment”) is entered into as of April 17, 2018 by and among ROSETTA GENOMICS INC., a Delaware corporation (“Borrower”), ROSETTA GENOMICS LTD., a company incorporated under the Laws of the State of Israel (“Rosetta” and, together with Borrower, each a “Guarantor” and collectively, jointly and severally the “Guarantors”; and together with Borrower, each a “Credit Party” and collectively, jointly and severally, the “Credit Parties”), and GENOPTIX, INC., as Lender (in such capacity, together with its successors and assigns, if any, in such capacity, “Lender”).

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AMENDMENT NO. 2 TO EXPENSE REIMBURSEMENT WAIVER AGREEMENT
Expense Reimbursement Waiver Agreement • April 19th, 2018 • Rosetta Genomics Ltd. • Pharmaceutical preparations • New York

This AMENDMENT NO. 2, dated as of April 17, 2018 (“Amendment No. 2”), to the Expense Reimbursement Waiver Agreement (as amended, the “Agreement”), dated as of February 27, 2018, by and between Rosetta Genomics Ltd., an Israeli corporation with a principal place of business at 10 Plaut Street, Science Park, Rehovot 76706, Israel (the “Company”) and Genoptix, Inc., a Delaware corporation with a principal place of business at 2131 Faraday Avenue, Carlsbad, California 92008 (“Parent”), is entered into by and between the Company and Parent. Capitalized terms used in this Amendment No. 2 and not otherwise defined herein shall have the meanings set forth in the Agreement.

AMENDMENT NO. 2 TO AGREEMENT AND PLAN OF MERGER
Agreement and Plan of Merger • April 19th, 2018 • Rosetta Genomics Ltd. • Pharmaceutical preparations • New York

This AMENDMENT NO. 2, dated as of April 17, 2018 (“Amendment No. 2”), to the Agreement and Plan of Merger, dated as of February 27, 2018 (as amended, the “Agreement”), by and among Genoptix, Inc., a Delaware corporation (“Parent”), Stone Marger Sub, Ltd., a company incorporated under the Laws of the State of Israel (“Merger Sub”), and Rosetta Genomics Ltd., a company incorporated under the Laws of the State of Israel (the “Company”), is entered into by and among Parent, the Company, and Merger Sub. Capitalized terms used in this Amendment No. 2 and not otherwise defined herein shall have the meanings set forth in the Agreement.

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