SECURITY AGREEMENTSecurity Agreement • May 14th, 2019 • Aevi Genomic Medicine, Inc. • Biological products, (no disgnostic substances) • New York
This SECURITY AGREEMENT (this “Agreement”) is dated as of March 29, 2019 and entered into by and Aevi Genomic Medicine, Inc., a Delaware corporation (“Aevi”), each of the undersigned direct and indirect Subsidiaries of Aevi (each of such undersigned Subsidiaries being a “Subsidiary Grantor” and, collectively, the “Subsidiary Grantors”) and each Additional Grantor that may become a party hereto after the date hereof in accordance with Section 21 hereof (each of Aevi and each Additional Grantor being a “Grantor” and collectively the “Grantors”) and The Children’s Hospital of Philadelphia (the “Secured Party”).
Aevi Genomic Medicine, Inc. 435 Devon Park Drive, Suite 715 Wayne, Pennsylvania 19087Agreement • May 14th, 2019 • Aevi Genomic Medicine, Inc. • Biological products, (no disgnostic substances) • Pennsylvania
This letter agreement (this “Agreement”) serves to formalize certain covenants made in the Agreement by and between Aevi Genomic Medicine, Inc. (“Aevi”) and The Children’s Hospital of Philadelphia (“CHOP”) on March 25, 2019. Reference is also made to: (i) that certain Sponsored Research Agreement, dated November 12, 2014, by and between Medgenics Medical Israel Ltd. ("Medgenics") and CHOP, as amended to date (the “SRA”), (ii) that certain License Agreement, dated November 12, 2014, by and between Medgenics and CHOP, as amended to date, (iii) that certain License Agreement, dated September 9, 2015, by and between neuroFix, LLC and CHOP, as amended to date, (iv) that certain License Agreement, dated December 18, 2017, by and between Aevi and CHOP, as amended to date, (v) that certain License Agreement, dated October 3, 2016, by and between Medgenics, Inc. and CHOP, as amended to date and (vi) that certain License Agreement, dated October 20, 2016, by and between Medgenics, Inc. and CHOP,
AMENDMENT NO. 1 TO LICENSE AGREEMENTLicense Agreement • May 14th, 2019 • Aevi Genomic Medicine, Inc. • Biological products, (no disgnostic substances)
This Amendment No. 1 to License Agreement (this “Amendment”) is made and entered into as of March 29, 2019 (the “Amendment Date”), by and between Neurofix LLC (“Licensee”), a limited liability company and wholly owned subsidiary of Aevi Genomic Medicine, Inc. (“Aevi”), a Delaware corporation, and The Children’s Hospital of Philadelphia, a non-profit entity organized and existing under the laws of Pennsylvania (“CHOP”). CHOP and Licensee are sometimes referred to in this Amendment individually as a “Party” and collectively as the “Parties.”
AMENDMENT NO. 3 TO SPONSORED RESEARCH AGREEMENTSponsored Research Agreement • May 14th, 2019 • Aevi Genomic Medicine, Inc. • Biological products, (no disgnostic substances)
This Amendment No. 3 to Sponsored Research Agreement (this “Amendment”) is made and entered into as of March 29, 2019 (the “Amendment Date”), by and between Medgenics Medical Israel Ltd. (“Sponsor”) , a company organized under the laws of the State of Israel and wholly owned subsidiary of Aevi Genomic Medicine, Inc., a Delaware corporation (“Aevi”), and The Children’s Hospital of Philadelphia, a non-profit entity organized and existing under the laws of Pennsylvania (“CHOP”). CHOP and Sponsor are sometimes referred to in this Amendment individually as a “Party” or, collectively, as the “Parties.”
AMENDMENT NO. 2 TO LICENSE AGREEMENTLicense Agreement • May 14th, 2019 • Aevi Genomic Medicine, Inc. • Biological products, (no disgnostic substances)
This Amendment No. 2 to License Agreement (this “Amendment”) is made and entered into as of March 29, 2019 (the “Amendment Date”), by and between Medgenics Medical Israel Ltd. (“Licensee”) , a company organized under the laws of the State of Israel and wholly owned subsidiary of Aevi Genomic Medicine, Inc., a Delaware corporation (“Aevi”), and The Children’s Hospital of Philadelphia, a non-profit entity organized and existing under the laws of Pennsylvania (“CHOP”). CHOP and Licensee are sometimes referred to in this Amendment individually as a “Party” and collectively as the “Parties.”
