0001157523-07-002699 Sample Contracts

AMENDMENT No. 2 to LICENSE AGREEMENT
License Agreement • March 15th, 2007 • Pathogenics, Inc. • Medicinal chemicals & botanical products

Amendment No. 2 to License (this “Amendment”) made as of March 8, 2007, by and between Acuity Pharmaceuticals, Inc., a Delaware corporation, with its principal offices at 3701 Market Street, Philadelphia, PA, 19104 (“Acuity”) and Pathogenics, Inc., a Delaware Corporation with its principal offices at 99 Derby Street, Suite 200, Hingham, MA 02043 (“Pathogenics”).

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AMENDMENT NO. 1 TO LICENSE AGREEMENT
License Agreement • March 15th, 2007 • Pathogenics, Inc. • Medicinal chemicals & botanical products

Amendment No. 1 to License (this “Amendment”) made as of August 2, 2006, by and between Acuity Pharmaceuticals, Inc., a Delaware corporation, with its principal offices at 3701 Market Street, Philadelphia, PA, 19104 (“Acuity”) and Pathogenics, Inc., a Delaware Corporation with its principal offices at 99 Derby Street, Suite 200, Hingham, MA 02043 (“Pathogenics”).

SECOND AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2007 • Pathogenics, Inc. • Medicinal chemicals & botanical products

THIS SECOND AMENDMENT (the “Second Amendment”) to the EMPLOYMENT AGREEMENT (the “Agreement”), is made in Hingham, Massachusetts as of the 1st day of January 2007, between Pathogenics, Inc. a Delaware corporation having its executive offices and principal place of business at 99 Derby Street, Suite 200, Hingham, MA 02043 (the “Company”), and Frederic P. Zotos, an individual currently residing at 1623 Avalon Drive, Hull, MA 02045 (“Employee”).

FIRST AMENDMENT TO CONSULTANCY AGREEMENT
Consultancy Agreement • March 15th, 2007 • Pathogenics, Inc. • Medicinal chemicals & botanical products

THIS FIRST AMENDMENT (the “First Amendment”) to the CONSULTANCY AGREEMENT (the “Agreement”), is made in Hingham, Massachusetts as of the 1st day of January, 2007, by and between Pathogenics, Inc. a Delaware corporation having its executive offices and principal place of business at 99 Derby Street, Suite 200, Hingham, MA 02043 (the “Corporation”), and Michael L. Ferrari (the “Consultant”), an individual residing at 6488 84th Street, Middle Vlg, NY 11379.

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