0001157523-12-001200 Sample Contracts

THIRD AMENDMENT TO JOINT DEVELOPMENT AND LICENSE AGREEMENT
Joint Development and License Agreement • March 2nd, 2012 • Dyax Corp • Services-commercial physical & biological research

This THIRD AMENDMENT (the "Third Amendment"), dated as of December 26, 2011 (the "Third Amendment Date"), is entered into by and between Dyax Corp., with effective offices at 300 Technology Square, Cambridge, Massachusetts 02139, U.S.A. ("Dyax"), and DefianteFarmacêutica S.A., with registered offices at Rua da Alfândega, n. 78, 3° andar, 9000-059, Funchal, Madeira, Portugal ("Defiante"). This Third Amendment further amends that certain Joint Development and License Agreement (the "Original Agreement"), dated effective as of June 18, 2010 (the "Effective Date"), as amended by the First Amendment to Joint Development and License Agreement (the "First Amendment”), dated December 21, 2010 (the "First Amendment Date") and the Second Amendment to Joint Development and License Agreement (the "Second Amendment"), dated May 21, 2011 (the "Second Amendment Date"). The Original Agreement, as amended by the First Amendment and the Second Amendment, is referred to herein as the "Amended Agreement."

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AMENDMENT TO SERVICES AGREEMENT (Specialty Pharmacy and Hub Services)
Services Agreement • March 2nd, 2012 • Dyax Corp • Services-commercial physical & biological research

This Amendment to the Services Agreement (this “Amendment”) is made and entered into as of February 15, 2011 (the “Amendment Effective Date”), by and between DYAX CORP. (“Dyax”) and US BIOSERVICES CORPORATION (“US Bio”).

AMENDMENT TO SERVICES AGREEMENT (Specialty Pharmacy and Hub Services)
Services Agreement • March 2nd, 2012 • Dyax Corp • Services-commercial physical & biological research

This Amendment to the Services Agreement (this “Amendment”) is made and entered into as of May 31, 2011 (the “Amendment Effective Date”), by and between DYAX CORP. (“Dyax”) and US BIOSERVICES CORPORATION (“US Bio”).

Dyax Corp. has requested that portions of this document be accorded confidential treatment pursuant to Rule 24b-2 promulgated under the Securities Exchange Act of 1934, as amended.
Loan Agreement • March 2nd, 2012 • Dyax Corp • Services-commercial physical & biological research • New York

This LOAN AGREEMENT (the “Agreement”), dated as of December 29, 2011, is entered into by and between LFRP INVESTORS, L.P., a Delaware limited partnership (the “Lender”), as Lender, and DYAX CORP., a Delaware corporation, as Borrower. The Lender and Borrower are hereinafter referred to collectively as the “Parties” or individually as a “Party.”

FIRST AMENDMENT TO LEASE
Lease • March 2nd, 2012 • Dyax Corp • Services-commercial physical & biological research

This First Amendment to Lease (“Amendment”) is made and entered into as of this 4th day of November, 2011 (the “Effective Date”) by and between NetView 5 and 6 LLC (“Landlord”) and Dyax Corp (“Tenant”).

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