Exhibit (a)(3)JPMorgan Chase Bank, N.A. - ADR Depositary • October 21st, 2022 • American depositary receipts • New York
Company FiledOctober 21st, 2022 Industry JurisdictionAMENDMENT NO. 2, dated as of ______ __, 2022 (the "Amendment"), to the Deposit Agreement, dated as of November 12, 2021 (as amended from time to time, the "Deposit Agreement"), among RELIEF THERAPEUTICS HOLDING SA and its successors (the “Company”), JPMorgan Chase Bank, N.A., as depositary (the "Depositary"), and all Holders and Beneficial Owners from time to time of American depositary receipts ("ADRs") issued thereunder evidencing American Depositary Shares (“ADSs”).