0001171843-20-006746 Sample Contracts

AMENDMENT #2 TO THE SENIOR SECURED
Senior Secured Promissory Note Amendment • September 30th, 2020 • Predictive Oncology Inc. • Orthopedic, prosthetic & surgical appliances & supplies

THIS AMENDMENT #2 to the Note (as defined below) (the "Amendment") is entered into as of September 30, 2020 (the "Effective Date"), by and between Predictive Oncology, Inc. (f/k/a Precision Therapeutics, Inc.), a Delaware corporation (the "Company"), and Oasis Capital, LLC, a Puerto Rico limited liability company (the "Holder", and together with the Company, the "Parties").

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AMENDMENT #3 TO THE SENIOR SECURED
Senior Secured Promissory Note Amendment • September 30th, 2020 • Predictive Oncology Inc. • Orthopedic, prosthetic & surgical appliances & supplies

THIS AMENDMENT #3 to the Note (as defined below) (the “Amendment”) is entered into as of September 30, 2020 (the "Effective Date"), by and between Predictive Oncology, Inc. (f/k/a Precision Therapeutics, Inc.), a Delaware corporation (the "Company"), and Oasis Capital, LLC, a Puerto Rico limited liability company (the “Holder”, and together with the Company, the "Parties").

AMENDMENT #5 TO THE SENIOR SECURED
Senior Secured Promissory Note Amendment • September 30th, 2020 • Predictive Oncology Inc. • Orthopedic, prosthetic & surgical appliances & supplies

THIS AMENDMENT #5 to the Note (as defined below) (the "Amendment") is entered into as of September 30, 2020 (the "Effective Date"), by and between Predictive Oncology, Inc. (f/k/a Precision Therapeutics, Inc.), a Delaware corporation (the "Company"), and L2 Capital, LLC, a Kansas

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