0001178670-24-000041 Sample Contracts

ALNYLAM PHARMACEUTICALS, INC. Performance Stock Unit Award Agreement Granted Under 2018 Stock Incentive Plan
Performance Stock Unit Award Agreement • August 1st, 2024 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations

Pursuant to the Alnylam Pharmaceuticals, Inc. 2018 Stock Incentive Plan, as amended through the date hereof (the “Plan”), Alnylam Pharmaceuticals, Inc. (the “Company”) hereby grants an award of the number of Performance Stock Units listed above (this “Award”) to the Grantee named above on the Grant Date. Each Performance Stock Unit shall relate to one share of common stock, par value $0.01 per share (the “Stock”) of the Company. Unless earlier terminated, this Award shall have a term of [______ (___)] years from the Grant Date.

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ALNYLAM PHARMACEUTICALS, INC. Restricted Stock Unit Award Agreement Granted Under 2018 Stock Incentive Plan
Restricted Stock Unit Award Agreement • August 1st, 2024 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations

Pursuant to the Alnylam Pharmaceuticals, Inc. 2018 Stock Incentive Plan, as amended through the date hereof (the “Plan”), Alnylam Pharmaceuticals, Inc. (the “Company”) hereby grants an award of the number of Restricted Stock Units listed above (this “Award”) to the Grantee named above on the Grant Date. Each Restricted Stock Unit shall relate to one share of common stock, par value $0.01 per share (the “Stock”) of the Company.

ALNYLAM PHARMACEUTICALS, INC. Nonstatutory Stock Option Agreement Granted Under 2018 Stock Incentive Plan
Nonstatutory Stock Option Agreement • August 1st, 2024 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations

Participant: [ ] ID: [ ] Award Number: [ ] Exercise Price Per Share: [ ] Grant Date: [ ] Vesting Commencement Date: [ ] Expiration Date: [ ] Number of Shares/Units: [ ]

ALNYLAM PHARMACEUTICALS, INC. Nonstatutory Stock Option Agreement Granted Under 2018 Stock Incentive Plan
Nonstatutory Stock Option Agreement • August 1st, 2024 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations

Participant: [ ] ID: [ ] Award Number: [ ] Exercise Price Per Share: [ ] Grant Date: [ ] Vesting Commencement Date: [ ] Expiration Date: [ ] Number of Shares/Units: [ ]

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