0001193125-03-091195 Sample Contracts

ELESTAT™ (EPINASTINE) CO-PROMOTION AGREEMENT
Inspire Pharmaceuticals Inc • December 9th, 2003 • Pharmaceutical preparations • Delaware

THIS ELESTAT™ (EPINASTINE) CO-PROMOTION AGREEMENT is entered into as of December 8th, 2003 by and between ALLERGAN SALES, LLC., a Delaware limited liability company (formerly ALLERGAN SALES, INC., a Delaware corporation), having an address of 2525 Dupont Drive, Irvine, California 92612 (hereinafter referred to as “ALLERGAN”), and INSPIRE PHARMACEUTICALS, INC., a Delaware corporation, having an address of 4222 Emperor Boulevard, Suite 200, Durham, North Carolina 27703 (hereinafter referred to as “INSPIRE”).

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FIRST AMENDMENT TO LICENSE, DEVELOPMENT AND MARKETING AGREEMENT
License, Development and Marketing Agreement • December 9th, 2003 • Inspire Pharmaceuticals Inc • Pharmaceutical preparations

This First Amendment to License, Development and Marketing Agreement (this “Amendment”) dated December 8, 2003 between INSPIRE PHARMACEUTICALS, INC., a Delaware corporation, having an address of 4222 Emperor Boulevard, Suite 470, Durham, North Carolina 27703 (“INSPIRE”) and ALLERGAN, INC., a Delaware corporation, having an address of 2525 Dupont Drive, Irvine, California 92612 and its Affiliates Allergan Sales, LLC. (formerly Allergan Sales, Inc.) and Allergan Pharmaceuticals Holdings (Ireland) Ltd. (collectively “ALLERGAN,” and together with INSPIRE, the “Parties”).

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