0001193125-04-033437 Sample Contracts

NUVELO, INC. 5,000,000 Shares Common Stock ($0.001 par value per Share) UNDERWRITING AGREEMENT
Underwriting Agreement • March 3rd, 2004 • Nuvelo Inc • In vitro & in vivo diagnostic substances • New York

Nuvelo, Inc., a Nevada corporation (the “Company”), proposes to issue and sell to the underwriters named in Schedule A annexed hereto (the “Underwriters”), for whom you are acting as representatives, an aggregate of 5,000,000 shares (the “Firm Shares”) of common stock, $0.001 par value per share (the “Common Stock”), of the Company. In addition, solely for the purpose of covering over-allotments, the Company proposes to grant to the Underwriters the option to purchase from the Company up to an additional 750,000 shares of Common Stock (the “Additional Shares”). The Firm Shares and the Additional Shares are hereinafter collectively sometimes referred to as the “Shares.” The Shares are described in the Prospectus which is referred to below.

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