0001193125-04-039259 Sample Contracts

OFFICE LEASE SIERRA POINT DEVELOPMENT GAINEY ONE TRUST, a Maryland real estate investment trust, as Landlord, and COTHERIX, INC., a Delaware corporation, as Tenant.
Office Lease • March 11th, 2004 • Cotherix Inc • California

This Office Lease (the “Lease”), dated as of the date set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), below, is made by and between GAINEY ONE TRUST, a Maryland real estate investment trust (“Landlord”), and COTHERIX, INC., a Delaware corporation (“Tenant”).

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INDEMNIFICATION AGREEMENT
Indemnification Agreement • March 11th, 2004 • Cotherix Inc • Delaware

This Indemnification Agreement (“Agreement”) is made as of [DATE] by and between CoTherix, Inc., a Delaware corporation (the “Company”), and [ ] (“Indemnitee”).

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • March 11th, 2004 • Cotherix Inc • California

This Executive Employment Agreement (“Agreement”) is entered into and employment (in the below capacities) shall commence pursuant to its terms as of October 8, 2003 (the “Employment Date”), by and between CoTherix, Inc. (formerly known as Exhale Therapeutics, Inc.) a Delaware corporation (the “Company”), and Donald Santel (the “Executive”), collectively herein the “Parties.”

DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • March 11th, 2004 • Cotherix Inc • New York

THIS AGREEMENT is made the 2nd day of October 2003 by and between Exhale Therapeutics, Inc., a U.S. corporation having its principal place of business at 1301 Shoreway Road, Suite 320, Belmont, California 94002, U.S.A. (hereinafter referred to as “Exhale”) and Schering Aktiengesellschaft, a corporation organized and existing under the laws of Germany having its principal place of business at Muellerstraße 178, 13353 Berlin, Germany (hereinafter referred to as “Schering”). Schering and Exhale are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

COTHERIX, INC. Second Amended and Restated Investor Rights Agreement
Investor Rights Agreement • March 11th, 2004 • Cotherix Inc • California

This Second Amended and Restated Investor Rights Agreement (this “Agreement”), dated as of October 8, 2003, is entered into by and among (i) CoTherix, Inc., a Delaware corporation (the “Company”), (ii) the holders of Preferred Stock of the Company listed on Schedule A attached hereto and (iii) the holders of Common Stock of the Company listed on Schedule B attached hereto.

EXHALE THERAPEUTICS, INC. Exclusive License Agreement
Exclusive License Agreement • March 11th, 2004 • Cotherix Inc • New York

AGREEMENT, dated as of March 14, 2000 (the “Effective Date”), between THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, a New York corporation (“Columbia”), and EXHALE THERAPEUTICS, INC., a Delaware corporation (the “Company”).

STANDARD LEASE AGREEMENT by and between F & S PROPERTIES, LLC (“Lessor”) and COTHERIX, INC. (“Lessee”)
Standard Lease • March 11th, 2004 • Cotherix Inc • California

This STANDARD LEASE (“Lease”) is entered into as of December 17, 2003, by and between F & S PROPERTIES, LLC, California Limited Liability Company (“Lessor”), and COTHERIX, INC., a Delaware corporation. (“Lessee”).

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