0001193125-04-068499 Sample Contracts

EXCLUSIVE LICENSE AGREEMENT between THE REGENTS OF THE UNIVERSITY OF CALIFORNIA and SALMEDIX, INC. for
Exclusive License Agreement • April 23rd, 2004 • Salmedix Inc • California

This exclusive license agreement (“Agreement”) is made effective this 21th day of September, 2001 (“Effective Date”), between The Regents of the University of California, a California corporation, having its statewide administrative offices at 1111 Franklin Street, 12th Floor, Oakland, California 94607-5200 (“The Regents”), and Salmedix, Inc., a Delaware corporation, having a principal place of business at 4330 La Jolla Village Drive, Suite 250, San Diego, California 92122 (“Licensee”).

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Contract
License Agreement • April 23rd, 2004 • Salmedix Inc

Confidential Materials omitted and field separately with the Securities and Exchange Commission. Asterisks denote such omissions.

Solutia Pharmaceutical Services Division GLOBAL SERVICES AGREEMENT BETWEEN AMCIS AG AND Fujisawa Deutschland GmbH AND Salmedix, Inc. Page 1 of 27
Salmedix Inc • April 23rd, 2004

This Supplement is attached to and made part of the Global Services Agreement (the “Services Agreement”), and is made this 28th day of February, 2004 between:

FORM OF REPURCHASE AGREEMENT
Form of Repurchase Agreement • April 23rd, 2004 • Salmedix Inc • California

This Repurchase Agreement (“Agreement”) is made and entered into as of June 5, 2002 by and among Salmedix, Inc., a Delaware corporation (the “Company”), (the “Investor”) and , the Investor’s spouse (the “Investor’s Spouse”). This Agreement inures to the benefit of each of the Company’s future parents, subsidiaries, related entities, and their predecessors, successors, officers, directors, stockholders, agents, employees and assigns.

Contract
Loan and Security Agreement • April 23rd, 2004 • Salmedix Inc

This LOAN AND SECURITY AGREEMENT (this “Agreement”) dated the Effective Date between SILICON VALLEY BANK (“Bank”) and SALMEDIX, INC. (“Borrower”), provides the terms on which Bank will lend to Borrower and Borrower will repay Bank. The parties agree as follows:

Void after the Tenth Anniversary hereof WARRANT FOR THE PURCHASE OF SHARES OF COMMON STOCK of SALMEDIX, INC. INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE
Salmedix Inc • April 23rd, 2004 • Delaware

THIS CERTIFIES THAT, for value received, ALEXANDRIA EQUITIES, LLC a Delaware limited liability company, together with its successors and assigns (the “Investor”), is entitled to purchase, up to Thirty Seven Thousand Five Hundred (37,500) duly authorized, validly issued, fully paid and nonassessable shares of Common Stock (the “Common Stock”) of SALMEDIX, INC., a Delaware corporation (the “Company”), at the per share purchase price described in Section 1.3 below, subject to the provisions and upon the terms and conditions hereinafter set forth.

SALMEDIX, INC. AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT March 30, 2004
Investors’ Rights Agreement • April 23rd, 2004 • Salmedix Inc • California

THIS AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT is made as of the 30th day of March, 2004, by and among Salmedix, Inc., a Delaware corporation (the “Company”), and the investors listed on Schedule A hereto (each, an “Investor” and collectively, the “Investors”). This Agreement amends and restated that certain Amended and Restated Investors’ Rights Agreement dated as of June 5, 2002, as amended through the date hereof (the “Prior Agreement”), by and among the Company and certain of the Investors.

FORM OF INDEMNIFICATION AGREEMENT
Form of Indemnification Agreement • April 23rd, 2004 • Salmedix Inc • Delaware

THIS INDEMNIFICATION AGREEMENT (the “Agreement”), effective as of April , 2004, is made between Salmedix, Inc., a Delaware corporation (the “Corporation”), and [ ] (the “Indemnitee”),

SUBLEASE
Sublease • April 23rd, 2004 • Salmedix Inc

THIS LEASE (“Lease”) is made as of February 18, 2000, by and between UNIVERSITY CENTER LLC, a California limited liability company (“Landlord”), and IDUN PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

Contract
Salmedix Inc • April 23rd, 2004 • California

THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR UNDER ANY APPLICABLE STATE SECURITIES LAWS. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED IN THE ABSENCE OF A REGISTRATION STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES UNDER SUCH ACT OR AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED OR UNLESS SOLD PURSUANT TO AN EXEMPTION TO SUCH ACT.

CONSULTING AGREEMENT
Consulting Agreement • April 23rd, 2004 • Salmedix Inc • California
WARRANT TO PURCHASE STOCK
Warrant to Purchase Stock • April 23rd, 2004 • Salmedix Inc • California

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AND PURSUANT TO THE PROVISIONS OF ARTICLE 5 BELOW, MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND APPLICABLE STATE SECURITIES LAW OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER OF THESE SECURITIES, SUCH OFFER, SALE OR TRANSFER, PLEDGE OR HYPOTHECATION IS EXEMPT FROM REGISTRATION.

SALMEDIX LETTERHEAD]
Salmedix Inc • April 23rd, 2004

This letter will serve as the basis by which you will be employed by Salmedix, Inc. (the “Company”) as its Chief Executive Officer.

SALMEDIX, INC. FORM OF RESTRICTED STOCK ISSUANCE AGREEMENT
Restricted Stock Issuance Agreement • April 23rd, 2004 • Salmedix Inc • California

This RESTRICTED STOCK ISSUANCE AGREEMENT (this “Agreement”) is made as of this day of 2000/2001, by and among Salmedix, Inc., a Delaware corporation (the “Corporation”), , an individual resident of the State of (“Individual”) and , the Individual’s spouse.

SECURITY AGREEMENT
Security Agreement • April 23rd, 2004 • Salmedix Inc • California

THIS SECURITY AGREEMENT dated as of February 12, 2002 (“Security Agreement”), is made by SALMEDIX, INC., a Delaware corporation (“Grantor”), in favor of ALEXANDRIA FINANCE, LLC, a Delaware limited liability company (“Secured Party”).

SALMEDIX, INC. AMENDED AND RESTATED STOCKHOLDERS’ AGREEMENT March 30, 2004
Stockholders’ Agreement • April 23rd, 2004 • Salmedix Inc • California

This Amended and Restated Stockholders’ Agreement (this “Agreement”) is made as of the 30th day of March, 2004 by and among Salmedix, Inc., a Delaware corporation (the “Company”), the initial stockholders of the Company listed on Schedule A attached hereto (collectively, the “Founders” and individually, a “Founder”), certain holders of Series A Preferred Stock listed on Schedule A attached hereto (the “Series A Holders”), certain holders of Series B Preferred Stock listed on Schedule A attached hereto (the “Series B Holders”) and certain holders of Series C Preferred Stock as well as the holder (the “Holder”) of a warrant to purchase shares of Series C Preferred Stock (the “Warrant”) listed on Schedule A attached hereto (collectively, and including the Holder to the extent such Warrant has been exercised, the “Series C Holders”). The Series A Holders, the Series B Holders and the Series C Holders are collectively referred to herein as the “Stockholders” and individually as a “Stockhold

CONSULTING AGREEMENT
Consulting Agreement • April 23rd, 2004 • Salmedix Inc
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