0001193125-04-135257 Sample Contracts

AMENDMENT TO THE DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • August 9th, 2004 • Trimeris Inc • Biological products, (no disgnostic substances)

This AMENDMENT TO THE DEVELOPMENT AND LICENSE AGREEMENT (“Amendment”) is executed on this 12th day of July 2004 to be effective the 5th day of January 2004, by and between Trimeris, Inc. (“Trimeris”), and F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. (collectively, “Roche”).

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EXECUTIVE EMPLOYMENT AGREEMENT
Separation and Severance Agreement • August 9th, 2004 • Trimeris Inc • Biological products, (no disgnostic substances) • North Carolina

THIS AGREEMENT is made and entered into this the 21st day of June, 2004, by and between TRIMERIS, INC., a Delaware corporation (the “Company”), and GEORGE W. (“BARNEY”) KOSZALKA (“Executive”).

RESCISSION OF THE AMENDMENT TO THE DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • August 9th, 2004 • Trimeris Inc • Biological products, (no disgnostic substances)

This RESCISSION OF THE AMENDMENT TO THE DEVELOPMENT AND LICENSE AGREEMENT is executed on this 12th day of July 2004, by and between Trimeris, Inc. (“Trimeris”), and F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. (collectively, “Roche”).

LEASE AGREEMENT BY AND BETWEEN PPD PHARMACO, INC., as Tenant AND WEEKS REALTY, L.P., as Landlord
Lease Agreement • August 9th, 2004 • Trimeris Inc • Biological products, (no disgnostic substances) • North Carolina

THIS LEASE AGREEMENT (the “Lease”), is made and entered into as of the 16th day of December, 1998, by and between WEEKS REALTY, L.P., a Georgia limited partnership authorized to do business in North Carolina as WEEKS REALTY LIMITED PARTNERSHIP (the “Landlord”), and PPD PHARMACO, INC., a Texas corporation (the “Tenant”).

SETTLEMENT AGREEMENT AND RELEASE
Settlement Agreement and Release • August 9th, 2004 • Trimeris Inc • Biological products, (no disgnostic substances) • North Carolina

THIS SETTLEMENT AGREEMENT AND RELEASE (“Settlement Agreement”) sets out the complete agreement and understanding between TRIMERIS, INC. (the “Company”) and M. NIXON ELLIS (the “Executive”) regarding the termination of Executive’s employment with the Company.

SUBLEASE
Sublease • August 9th, 2004 • Trimeris Inc • Biological products, (no disgnostic substances) • North Carolina

THIS SUBLEASE (“Sublease”), made this 30th day of June, 2004, by and between PPD DEVELOPMENT, LP, a Texas limited partnership (“Sublessor”), and Trimeris, Inc., a Delaware corporation (“Sublessee”).

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