0001193125-04-139249 Sample Contracts

COUNTY OF DURHAM FOURTH AMENDMENT TO LEASE
Inspire Pharmaceuticals Inc • August 12th, 2004 • Pharmaceutical preparations

THIS FOURTH AMENDMENT TO LEASE (the “Fourth Amendment”) is made and entered into as of the 4th day of August, 2004, by and between ROYAL CENTER IC, LLC, a Delaware limited liability company (“Landlord”) [successor-in-interest to Imperial Center Limited Partnership, a North Carolina limited partnership (“ICLP”)] and INSPIRE PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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COUNTY OF DURHAM THIRD AMENDMENT TO LEASE
Inspire Pharmaceuticals Inc • August 12th, 2004 • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE (the “Third Amendment”) is made and entered into as of the 4th day of August, 2004, by and between ROYAL CENTER IC, LLC, a Delaware limited liability company (“Landlord”) [successor-in-interest to Royal Center Two IC, LLC, a Delaware limited liability company (“RC Two”) and Petula Associates, Ltd., an Iowa corporation (“Petula”)] and INSPIRE PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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