0001193125-04-186114 Sample Contracts

THIRD SUPPLEMENTAL INDENTURE
Third Supplemental Indenture • November 4th, 2004 • Pacificare Health Systems Inc /De/ • Hospital & medical service plans • New York

This Third Supplemental Indenture (this “Third Supplemental Indenture”) dated as of January 14, 2004, by and between PacifiCare Health Systems, Inc., a Delaware corporation (the “Company”); PacifiCare Health Plan Administrators, Inc., an Indiana corporation, PacifiCare eHoldings, Inc., a California corporation, MEDeMORPHUS Healthcare Solutions, Inc. (formerly known as RxConnect, Inc.), a California corporation, SeniorCo, Inc., a Delaware corporation, Rx Solutions, Inc., a California corporation, PacifiCare Behavioral Health, Inc., a Delaware corporation, Secure Horizons USA, Inc., a California corporation, PacifiCare of Arizona, Inc., an Arizona corporation, and PacifiCare Oklahoma, Inc., an Oklahoma corporation (collectively, the “Existing Subsidiary Guarantors”); and PacifiCare Southwest Operations, Inc., a Delaware corporation (the “Additional Subsidiary Guarantor”); and U.S. Bank National Association, a national banking association, as successor to State Street Bank and Trust Compa

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SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • November 4th, 2004 • Pacificare Health Systems Inc /De/ • Hospital & medical service plans • New York

This Second Supplemental Indenture (this “Second Supplemental Indenture”) dated as of November 19, 2003, by and between PacifiCare Health Systems, Inc., a Delaware corporation (the “Company”); PacifiCare Health Plan Administrators, Inc., an Indiana corporation, PacifiCare eHoldings, Inc., a California corporation, MEDeMORPHUS Healthcare Solutions, Inc. (formerly known as RxConnect, Inc.), a California corporation, and SeniorCo, Inc., a Delaware corporation (collectively, the “Initial Subsidiary Guarantors”); Rx Solutions, Inc., a California corporation, PacifiCare Behavioral Health, Inc., a Delaware corporation, and Secure Horizons USA, Inc., a California corporation (collectively, the “PHPA Subsidiary Guarantors”); PacifiCare of Arizona, Inc., an Arizona corporation, and PacifiCare Oklahoma, Inc., an Oklahoma corporation (collectively, the “Additional Subsidiary Guarantors”); and U.S. Bank National Association, a national banking association, as successor to State Street Bank and Trus

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