0001193125-04-187806 Sample Contracts

SECOND AMENDMENT TO LEASE AGREEMENT
Lease Agreement • November 5th, 2004 • Adherex Technologies Inc • Biological products, (no disgnostic substances)

THIS SECOND AMENDMENT TO LEASE (the “Second Amendment”) is entered into this 14th day of September 2004, by and between Realmark-Commercial LLC and (hereinafter called “Lessor”) and Adherex, Inc. (hereinafter called “Lessee”).

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Letterhead] Personal and Confidential
Employment Agreement • November 5th, 2004 • Adherex Technologies Inc • Biological products, (no disgnostic substances) • North Carolina

This letter is to offer you employment with Adherex, Inc. (the “Company”), a wholly owned subsidiary of Adherex Technologies Inc. (“AHX”), in Durham, North Carolina, conditional on your execution of the enclosed agreements. You will serve as Chief Scientific Officer of the Company and of AHX.

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