0001193125-05-005005 Sample Contracts

AAD DEVICE SUPPLY AGREEMENT
Aad Device Supply Agreement • January 12th, 2005 • Cotherix Inc • Biological products, (no disgnostic substances) • Delaware

This AAD Device Supply Agreement (“Agreement”) is made this day of December, 2004 by and between Profile Drug Delivery Ltd. with its principal place of business at Heath Place, Bognor Regis, West Sussex, PO22 9SL, United Kingdom, on the one hand (“Profile”) and CoTherix, Inc. with its principal place of business at 5000 Shoreline Court, Suite 101, South San Francisco, California 94080 (“CoTherix”), on the other hand.

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Schering AG CoTherix, Inc. Mr. Donald Santel CEO 5000 Shoreline Court Suite 101 South San Francisco, California 94080 U.S.A.
Cotherix Inc • January 12th, 2005 • Biological products, (no disgnostic substances)

We refer to the Development and License Agreement by and between CoTherix, Inc., South San Francisco, California (hereinafter “CoTherix” - formerly called ‘Exhale Therapeutics, Inc.’) and Schering dated October 2, 2003 as amended by Amendment # 1 dated November 4/22, 2004 (hereinafter the “Agreement”).

Schering AG CoTherix, Inc. Mr. Donald Santel CEO 5000 Shoreline Court Suite 101 South San Francisco, California 94080 U.S.A.
Cotherix Inc • January 12th, 2005 • Biological products, (no disgnostic substances)

We refer to the Development and License Agreement by and between CoTherix, Inc., Belmont, California (hereinafter “CoTherix” - formerly called ‘Exhale Therapeutics, Inc.’) and Schering dated October 2, 2003 (hereinafter the “License Agreement”), and the Manufacturing and Supply Agreement by and between CoTherix and Schering dated May 12/17, 2004 (hereinafter the “MSA”).

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