0001193125-05-013068 Sample Contracts

FORM OF GREEN SHOE OPTION AGREEMENT
Form of Green Shoe Option Agreement • January 27th, 2005 • Medicinova Inc • Pharmaceutical preparations

RELATING TO GREEN SHOE OPTION AGREEMENT (this “Agreement”) is made and entered into in Tokyo, Japan, as of , 2005 by and between MediciNova, Inc. (the “Company”) and Daiwa Securities SMBC Co. Ltd. (“Daiwa Securities SMBC”) acting as representative of the Underwriters (hereinafter defined) in connection with the granting, exercise of, and the issuance of shares (the “Optional Shares”) pursuant to, the green shoe option (the “Green Shoe Option”) set forth under Article 3 of the “MediciNova, Inc. 30,000,000 Shares of Common Stock Subscription Agreement” (the “Subscription Agreement”) entered into by and between the Company and Daiwa Securities SMBC as representative of the underwriters (the “Underwriters”) named therein and dated the date hereof in connection with the subscription and offering (the “Offering”) in Japan of 30,000,000 shares of common stock of the Company and the secondary offering by Daiwa Securities SMBC in Japan of 4,500,000 shares (the “Secondary Offering Shares by mean

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MediciNova, Inc. 30,000,000 Shares of Common Stock FORM OF SUBSCRIPTION AGREEMENT
Form of Subscription Agreement • January 27th, 2005 • Medicinova Inc • Pharmaceutical preparations

THIS SUBSCRIPTION AGREEMENT (this “Agreement”) is made and entered into in Tokyo, Japan, as of January 28, 2005 by and between MediciNova, Inc., a Delaware corporation (the “Company”), Daiwa Securities SMBC Co, Ltd. (the “Lead Manager”), acting as representative of the underwriters named in Schedule A (collectively, the “Underwriters”), concerning the subscription and offering in Japan and other jurisdictions outside the United States of 30,000,000 shares of common stock of the Company.

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