0001193125-05-105519 Sample Contracts

LOAN MODIFICATION AGREEMENT
Loan Modification Agreement • May 12th, 2005 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances)

This Loan Modification Agreement (this “Loan Modification Agreement’) dated as of April 7, 2004, by and between SILICON VALLEY BANK, a California-chartered bank, with its principal place of business at 3003 Tasman Drive, Santa Clara, California 95054 and with a loan production office located at One Newton Executive Park, Suite 200, 2221 Washington Street, Newton, Massachusetts 02462, doing business under the name “Silicon Valley East” (“Bank”) and GTC BIOTHERAPEUTICS, INC., a Massachusetts corporation with its chief executive office located at 175 Crossing Boulevard, Suite 410, Framingham, Massachusetts 01702 (“Borrower”).

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LOAN MODIFICATION AGREEMENT
Loan Modification Agreement • May 12th, 2005 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances)

This Loan Modification Agreement (this “Loan Modification Agreement”) is entered into as of January 25, 2004, by and between SILICON VALLEY BANK, a California-chartered bank, with its principal place of business at 3003 Tasman Drive, Santa Clara, California 95054 and with a loan production office located at One Newton Executive Park, Suite 200, 2221 Washington Street, Newton, Massachusetts 02462, doing business under the name “Silicon Valley East” (“Bank”) and GTC BIOTHERAPEUTICS, INC., a Massachusetts corporation with its chief executive office located at 175 Crossing Boulevard, Suite 410, Framingham, Massachusetts 01702 (“Borrower”).

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