0001193125-05-146419 Sample Contracts

FORM OF SECURITY AGREEMENT
Security Agreement • July 21st, 2005 • Biodelivery Sciences International Inc • Pharmaceutical preparations • New York

THIS SECURITY AGREEMENT (the “Agreement”), dated as of , 2005, among BioDelivery Sciences International, Inc. (“BioDelivery”), a corporation organized under the laws of the State of Delaware, Arius Pharmaceuticals, Inc., a Delaware corporation and wholly-owned subsidiary of BioDelivery (“Grantor”), and Clinical Development Capital LLC (“Secured Party”), a limited liability company organized under the laws of the State of Delaware.

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REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • July 21st, 2005 • Biodelivery Sciences International Inc • Pharmaceutical preparations • New York

THIS REGISTRATION RIGHTS AGREEMENT (“Agreement”) is entered into as of July 14, 2005, by and between BioDelivery Sciences International, Inc., a Delaware corporation (the “Company”) and Clinical Development Capital LLC, a Delaware limited liability company (the “Investor”).

CLINICAL DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • July 21st, 2005 • Biodelivery Sciences International Inc • Pharmaceutical preparations • New York

THIS CLINICAL DEVELOPMENT AND LICENSE AGREEMENT dated as of July 14, 2005 (the “Effective Date”), among Clinical Development Capital LLC (“CDC”), a limited liability company organized under the laws of the State of Delaware, having a business address at 47 Hulfish Street, Suite 310, Princeton, NJ 08542, BioDelivery Sciences International, Inc. (“BioDelivery”), a corporation organized under the laws of the State of Delaware, having a business address at 2501 Aerial Center Parkway, Suite 205, Morrisville, NC 27560, and Arius Pharmaceuticals, Inc., a Delaware corporation and wholly-owned subsidiary of BioDelivery (“Subsidiary”, and together with BioDelivery, the “Company”). CDC and Company are sometimes referred to herein individually as a “Party” and collectively as “Parties”.

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