0001193125-05-148106 Sample Contracts

MANUFACTURING AND SUPPLY AGREEMENT
Supply Agreement • July 25th, 2005 • Skinmedica Inc • Pharmaceutical preparations • California

THIS MANUFACTURING AND SUPPLY AGREEMENT is entered into effective as of June 30, 2002 (“Effective Date”), by and between ENHANCED DERM TECHNOLOGIES, INC., a Delaware corporation (“EDT”) and SKINMEDICA, INC., a California corporation (“SM”). EDT and SM are each referred to as a “Party” to this Agreement, and collectively as the “Parties.”

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SUPPLY AGREEMENT Between BRISTOL-MYERS SQUIBB COMPANY and SKINMEDICA, INC. for VANIQA® Dated as of May 14, 2004
Supply Agreement • July 25th, 2005 • Skinmedica Inc • Pharmaceutical preparations • New York

THIS SUPPLY AGREEMENT (this “Agreement”) dated as of May 14, 2004 (the “Agreement Date”), is between Bristol-Myers Squibb Company, a Delaware corporation (“BMS”), and SkinMedica, Inc., a Delaware corporation (the “Company”).

CONTRACT MANUFACTURING/PACKAGING AGREEMENT
Contract Manufacturing/Packaging Agreement • July 25th, 2005 • Skinmedica Inc • Pharmaceutical preparations • New York

THIS CONTRACT MANUFACTURING / PACKAGING AGREEMENT (this “Agreement”) made this 3rd day of November, 2003 (the “Effective Date”), by and between BRISTOL-MYERS SQUIBB COMPANY, a Delaware corporation with offices at 100 Forest Avenue, Buffalo, New York 14213 (“BMS”), and SKINMEDICA INC., a Delaware corporation with offices at 5909 Sea Lion Place, Suite H, Carlsbad, California 92008 (“SkinMedica”). BMS and SkinMedica are each a “Party” under this Agreement and both of them are referred to as “Parties” herein.

LICENSE AND SUPPLY AGREEMENT
License and Supply Agreement • July 25th, 2005 • Skinmedica Inc • Pharmaceutical preparations • Delaware

This Agreement dated this 31st day of March, 2003, by and between Cardinal Health P.R. 409 B.V. having its principal offices at Rd 925 Km 6.1, Bo. Junquito, Humacao PR 00791 (hereafter called “Cardinal Health”), and SkinMedica, Inc. (hereafter called “Purchaser”), having its principal offices at 5909 Sea Lion Place, Suite H, Carlsbad, CA 92008.

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