0001193125-05-164812 Sample Contracts

AMENDMENT TO LICENSE AGREEMENT
License Agreement • August 11th, 2005 • Senetek PLC /Eng/ • Biological products, (no disgnostic substances)

This Amendment (the “Amendment”) is made and entered into as of July 15, 2005 to the License Agreement made and entered into as of August 1, 2003, as amended from time to time (the “Agreement”), by and between Senetek PLC, an English corporation with its corporate headquarters located at 620 Airpark Road, Napa, California 94558 (“Senetek”), and Valeant Pharmaceuticals International, a Delaware corporation with its corporate headquarters located at 3300 Hyland Avenue, Costa Mesa, California 92626 (“Licensee”). Capitalized terms used herein and not otherwise defined are used with the meanings ascribed to them in the Agreement.

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