0001193125-05-221287 Sample Contracts

AMENDMENT NO. 1 TO EXCLUSIVE SALES DISTRIBUTION AGREEMENT
Exclusive Sales Distribution Agreement • November 9th, 2005 • Orthovita Inc • Surgical & medical instruments & apparatus • California

THIS AMENDMENT NO. 1 (“Amendment”) to that certain Exclusive Sales Distribution Agreement, dated July 1, 2004 (“Agreement”), is dated September 30, 2005 (“Amendment Effective Date”), and is between Orthovita, Inc., a Pennsylvania corporation with principal offices at 45 Great Valley Parkway, Malvern, Pennsylvania 19355 (“Orthovita”), and Angiotech BioMaterials Corp. (formerly known as Cohesion Technologies, Inc.), a Delaware corporation with principal offices at 2500 Faber Place, Palo Alto, California 94303 (“Cohesion”).

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