0001193125-05-249132 Sample Contracts

PACIFICARE HEALTH SYSTEMS, INC., POINT ACQUISITION LLC (to be renamed PacifiCare Health Systems, LLC), UNITEDHEALTH GROUP INCORPORATED and
First Supplemental Indenture • December 27th, 2005 • Pacificare Health Systems Inc /De/ • Hospital & medical service plans • New York

This FIRST SUPPLEMENTAL INDENTURE (this “First Supplemental Indenture”), dated as of December 20, 2005, is by and among PacifiCare Health Systems, Inc., a Delaware corporation (the “Company”), UnitedHealth Group Incorporated, a Minnesota corporation (“UnitedHealth Group”), Point Acquisition LLC, a limited liability company organized under the laws of the State of Delaware and a direct, wholly owned subsidiary of UnitedHealth Group (the “Successor Company”), and U.S. Bank National Association (as successor-in-interest to State Street Bank and Trust Company of California, N.A.), a national banking association (the “Trustee”).

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