0001193125-06-051219 Sample Contracts

Contract
Cv Therapeutics Inc • March 10th, 2006 • Biological products, (no disgnostic substances) • California

THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 AS AMENDED. THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE OF THIS WARRANT MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT AS TO THIS WARRANT OR THE SHARES ISSUABLE UPON EXERCISE OF THIS WARRANT, RESPECTIVELY, UNDER SAID ACT OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED.

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EMPLOYMENT AGREEMENT
Employment Agreement • March 10th, 2006 • Cv Therapeutics Inc • Biological products, (no disgnostic substances) • California

THIS EMPLOYMENT AGREEMENT (the “Agreement”), is made as of the 22nd day of December, 2005 (the “Effective Date”, by and between CV THERAPEUTICS, INC. (the “Company”) and LOUIS G. LANGE (the “Executive”).

Stock Appreciation Rights Agreement Grant Notice
Stock Appreciation Rights Agreement • March 10th, 2006 • Cv Therapeutics Inc • Biological products, (no disgnostic substances)

Exercise Schedule: Subject to the terms and conditions in Appendix A, this Award shall vest and be automatically exercised for the Stock Appreciation Rights in a series of four (4) successive equal annual installments upon Participant’s completion of each year of Service over the four (4)-year period measured from the Vesting Commencement Date. In no event shall this Award become vested and exercisable for any additional Stock Appreciation Rights after Employee’s cessation of Service.

SEVENTH AMENDMENT OF LEASE
Lease • March 10th, 2006 • Cv Therapeutics Inc • Biological products, (no disgnostic substances)

THIS SEVENTH AMENDMENT OF LEASE (“Seventh Amendment”) is made and entered into as of this 19th day of January 2006 (“Reference Date”), by and between the Wheatley Family Limited Partnership, a California Limited Partnership dba Matadero Creek, successor in interest to Jack R. Wheatley dba Matadero Creek, a sole proprietorship, (“Landlord”), and CV Therapeutics, Inc., a Delaware corporation (“Tenant”).

AMENDMENT NO. 1 CO-PROMOTION AGREEMENT
-Promotion Agreement • March 10th, 2006 • Cv Therapeutics Inc • Biological products, (no disgnostic substances)

This Amendment No. 1 to CO-PROMOTION AGREEMENT (hereinafter “Amendment”) is made on the 6th day of March, 2006, between Solvay Pharmaceuticals, Inc., a corporation organized and existing under the laws of the State of Georgia and having a principal place of business at 901 Sawyer Road, Marietta Georgia 30062, U.S.A. (hereinafter “Solvay”) and CV THERAPEUTICS, INC., a corporation organized and existing under the laws of the State of Delaware and having a principal place of business at 3172 Porter Drive, Palo Alto, California 94304, U.S.A. (hereinafter “CV Therapeutics”).

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