0001193125-06-054015 Sample Contracts

Contract
Manufacturing Service Agreement • March 15th, 2006 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts

Confidential material omitted and filed separately with the Securities and Exchange Commission. Asterisks denote such omissions.

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MASTER AGREEMENT RELATING TO THE PRODUCTION OF CLARIFIED GOAT’S MILK CONTAINING RECOMBINANT HUMAN ALPHA FETOPROTEIN BY AND BETWEEN GTC BIOTHERAPEUTICS, INC. AND MERRIMACK PHARMACEUTICALS, INC. September 9, 2005
Agreement • March 15th, 2006 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts

THIS AGREEMENT (the “Master Agreement”) is made this 9th day of September, 2005 (the “Effective Date”), by and between Merrimack Pharmaceuticals, Inc., a Massachusetts corporation (“Merrimack”) located at 101 Binney Street, Cambridge, MA 02142 and GTC Biotherapeutics, Inc., a Massachusetts corporation (“GTC”) located at 175 Crossing Boulevard, Framingham, MA 01702. (GTC and Merrimack each individually a “Party” and collectively the “Parties”).

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