0001193125-06-184278 Sample Contracts

NOTICE OF BREACH AND TERMINATION
Notice of Breach and Termination • September 1st, 2006 • CDC Iv LLC • Pharmaceutical preparations

We make reference to the Clinical Development and License Agreement dated as of July 14, 2005 among BioDelivery Sciences International, Inc. (“BDSI”), Clinical Development Capital LLC (together with its successors and assigns, “CDC”), and Arius Pharmaceuticals, Inc. (such agreement, as amended, the “CDLA”).

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