0001193125-06-221598 Sample Contracts

AMENDMENT TO OFFER LETTER
Offer Letter • November 2nd, 2006 • Curis Inc • Biological products, (no disgnostic substances) • Delaware

This Amendment (the “Amendment”), effective as of October 31, 2006 (the “Effective Date”), to the offer letter dated January 11, 2001 (the “Offer Letter”) by and between Curis, Inc., a Delaware corporation (the “Company”), and Mark W. Noel (the “Executive”).

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AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • November 2nd, 2006 • Curis Inc • Biological products, (no disgnostic substances) • Delaware

This Amendment (the “Amendment”), effective as of October 31, 2006 (the “Effective Date”), to the employment agreement executed on September 20, 2001 (the “Employment Agreement”) by and between Curis, Inc., a Delaware corporation (the “Company”), and Daniel R. Passeri (the “Executive”).

FIRST AMENDMENT TO CONSULTING AGREEMENT BY AND BETWEEN CURIS, INC. AND JOSEPH M. DAVIE, Ph.D., M.D. OCTOBER 30, 2006
Consulting Agreement • November 2nd, 2006 • Curis Inc • Biological products, (no disgnostic substances)

This First Amendment (“Amendment”), effective as of October 30, 2006 (“Amendment Date”), is made by and between Curis, Inc., having a place of business at 61 Moulton Street, Cambridge, MA 02138 (“Curis”), and Joseph M. Davie, Ph.D., M.D. (“Consultant”). Curis and Consultant may each be referred to individually as a “Party” and collectively as the “Parties.”

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