0001193125-07-009008 Sample Contracts

AMENDMENT NO. 3 to DEVELOPMENT AND LICENSE AGREEMENT between GLAXO GROUP LIMITED and ADHEREX TECHNOLOGIES INC.
Development and License Agreement • January 19th, 2007 • Adherex Technologies Inc • Biological products, (no disgnostic substances) • North Carolina

THIS AMENDMENT NO. 3 (this “Third Amendment”) effective on this 17th day of January, 2007 (the “Third Amendment Effective Date”), is entered into by and between Glaxo Group Limited, a company organized under the laws of England and Wales, having its registered office at GlaxoWellcome House, Berkeley Avenue, Greenford, Middlesex, UB6 0NN United Kingdom (“GGL”) and Adherex Technologies Inc., a company organized under the laws of Canada and having an office located at 4620 Creekstone Drive, Suite 200, Durham, North Carolina, 27703 USA (“Adherex”):

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