0001193125-07-054984 Sample Contracts

BAY COLONY CORPORATE CENTER WALTHAM, MASSACHUSETTS OFFICE LEASE BAY COLONY CORPORATE CENTER LLC, a Delaware limited liability company, Landlord and OSCIENT PHARMACEUTICALS CORPORATION, a Massachusetts corporation, Tenant DATED AS OF: June 23, 2004
Office Lease • March 15th, 2007 • Oscient Pharmaceuticals Corp • Pharmaceutical preparations • Massachusetts

THIS LEASE is made as of the 23 day of June, 2004, between BAY COLONY CORPORATE CENTER LLC, a Delaware limited liability company (“Landlord”), and OSCIENT PHARMACEUTICALS CORPORATION, a Massachusetts corporation (“Tenant”).

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Contract
Common Stock Purchase Warrant • March 15th, 2007 • Oscient Pharmaceuticals Corp • Pharmaceutical preparations

THIS SECURITY AND THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”) OR THE SECURITIES LAWS OF ANY STATE OR OTHER JURISDICTION AND MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED EXCEPT (1) PURSUANT TO AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OR (2) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT, IN EACH CASE IN ACCORDANCE WITH ALL APPLICABLE SECURITIES LAWS OF THE STATES AND OTHER JURISDICTIONS, AND IN THE CASE OF A TRANSACTION EXEMPT FROM REGISTRATION, UNLESS THE COMPANY HAS RECEIVED AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO IT THAT SUCH TRANSACTION DOES NOT REQUIRE REGISTRATION UNDER THE SECURITIES ACT AND SUCH OTHER APPLICABLE LAWS.

AMENDMENT NO. 7 TO LICENSE & OPTION AGREEMENT
License & Option Agreement • March 15th, 2007 • Oscient Pharmaceuticals Corp • Pharmaceutical preparations

THIS AMENDMENT NO. 7 TO THE LICENSE & OPTION AGREEMENT (“Amendment No. 7”) is made and entered into this 27th day of December, 2006 (the “Amendment No. 7 Effective Date”) by and between Oscient Pharmaceuticals Corporation (“OSCIENT”), a Massachusetts corporation, having a principal place of business at 1000 Winter Street, Suite 2200, Waltham, Massachusetts 02451, and LG Life Sciences, LTD (“LGLS”), a corporation organized under the laws of the Republic of Korea, having a principal place of business at LG Twin Tower, 20 yoido-dong, Youngdungpo-gu, Seoul, 150-721, Republic of Korea. LGLS and OSCIENT may be referred to herein individually as a “Party” and collectively as the “Parties”.

LICENSE, SUPPLY AND MARKETING AGREEMENT
License, Supply and Marketing Agreement • March 15th, 2007 • Oscient Pharmaceuticals Corp • Pharmaceutical preparations • England

THIS LICENSE, SUPPLY AND MARKETING AGREEMENT (this “Agreement”) is made effective as of December 28th, 2006 (the “Effective Date”) by and between Oscient Pharmaceuticals Corporation, a Massachusetts corporation with a principal place of business at 1000 Winter Street, Suite 2200, Waltham, Massachusetts (“Oscient”), Menarini International Operation Luxembourg SA, a Luxembourgian company with a place of business at 1, Avenue de La Gare, L-1611 Luxembourg GD (“MIOL”) Oscient and MIOL are each hereafter referred to individually as a “Party” and together as the “Parties”.

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • March 15th, 2007 • Oscient Pharmaceuticals Corp • Pharmaceutical preparations • New York

This REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made as of August 18, 2006, between Oscient Pharmaceuticals Corporation, a Massachusetts corporation (the “Company”), and Paul Royalty Fund Holdings II, a California general partnership (the “PRF”).

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