0001193125-07-057082 Sample Contracts

1 SCIENCE COURT OFFICE LEASE BETWEEN WARZYN BUILDING ASSOCIATES, LANDLORD AND NIMBLEGEN SYSTEMS, INC. AND NIMBLEGEN SYSTEMS, LLC, TENANT
Office Lease • March 16th, 2007 • Nimblegen Systems Inc • Wisconsin

THIS LEASE, made this 14th day of November, 2000, by and between WARZYN BUILDING ASSOCIATES, hereinafter referred to as the “Landlord”, and NIMBLEGEN SYSTEMS, INC. and NIMBLEGEN SYSTEMS, LLC, hereinafter collectively referred to as the “Tenant.”

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WARRANT TO PURCHASE 30,000 SHARES OF SERIES F PREFERRED STOCK
Nimblegen Systems Inc • March 16th, 2007 • Delaware

THIS CERTIFIES THAT, for value received, General Electric Capital Corporation (“Holder”) is entitled to subscribe for and purchase Thirty Thousand (30,000) shares of fully paid and nonassessable Series F Preferred Stock (collectively, the “Warrant Shares”) of NimbleGen Systems, Inc., a Delaware corporation (the “Company”), at the Warrant Price (as hereinafter defined), subject to the provisions and upon the terms and conditions hereinafter set forth. As used herein, the term “Preferred Stock” shall mean the Company’s presently authorized Series F Preferred Stock pursuant to its Eighth Amended and Restated Certificate of Incorporation, and any stock into which such Preferred Stock may hereafter be converted or exchanged and the term “Warrant Shares” shall mean the shares of Preferred Stock which Holder may acquire pursuant to this Warrant and any other shares of stock into which such shares of Preferred Stock may hereafter be converted or exchanged.

Contract
Agreement • March 16th, 2007 • Nimblegen Systems Inc • Delaware

This Agreement is made as of July 8, 2003 between GATX Ventures, Inc. (“Lender”) and Nimblegen Systems Inc. (“Borrower”). Reference is made to the Equipment Loan and Security Agreement dated as of June 6, 2002 (the “Loan Agreement”) between Lender and Borrower.

Contract
Nimblegen Systems Inc • March 16th, 2007

Vinlandslelö ehf, Reg. No. 601299-6239, Stangarhyl 5, Reykjavík, Iceland, hereafter referred to as the Lessor, and NimbleGen Systems of Iceland LLC –útibú a Ísandi, Reg. No. 68102-2790, Snorrabrault 60, Reykjavík, Iceland, hereafter referred to as the Lessee, hereby entering into the following:

STANDARD EXCLUSIVE LICENSE AGREEMENT
Standard Exclusive License Agreement • March 16th, 2007 • Nimblegen Systems Inc

This Agreement is made effective the 27th day of September, 1999, by and between Wisconsin Alumni Research Foundation (hereinafter called “WARF”), a nonstock, nonprofit Wisconsin corporation, and NimbleGen Systems LLC (hereinafter called “NimbleGen”), a limited liability company organized and existing under the laws of Wisconsin;

Contract
Nimblegen Systems Inc • March 16th, 2007

NOTE: The information designated by a bracketed asterisk [*] has been omitted pursuant to a request for confidential treatment and has been filed separately with the Securities and Exchange Commission.

STANDARD EQUITY AGREEMENT
Standard Equity Agreement • March 16th, 2007 • Nimblegen Systems Inc • Wisconsin

This Agreement is made effective the 27th day of September, 1999, by and between Wisconsin Alumni Research Foundation (hereinafter called “WARF”), a nonstock, nonprofit Wisconsin corporation, and NimbleGen Systems LLC (hereinafter called “NimbleGen”), a limited liability company organized and existing under the laws of Wisconsin;

NIMBLEGEN SYSTEMS, INC. SEVENTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT January 25, 2007
Registration Rights Agreement • March 16th, 2007 • Nimblegen Systems Inc • Wisconsin

This SEVENTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is dated as of January 25, 2007 by and among NIMBLEGEN SYSTEMS, INC., a Delaware corporation (the “Company”), and the individuals and entities listed on the signature pages hereof, and any other individuals or entities that may execute a counterpart signature page to this Agreement subsequent to the date hereof (collectively, the parties hereto and such other persons or entities are referred to herein as the “Preferred Stockholders”), and amends and restates the Sixth Amended and Restated Registration Rights Agreement dated as of December 22, 2006 (the “Amended Agreement”), by and among the Company and the individuals and entities listed on the signature pages thereof and any other individuals or entities that may have executed a counterpart signature page thereto.

AMENDMENT TO LICENSE AGREEMENT
License Agreement • March 16th, 2007 • Nimblegen Systems Inc

This Amendment is made effective as of the 24th day of April, 2000, by and between Wisconsin Alumni Research Foundation (“WARF”), a nonstock, nonprofit Wisconsin corporation, and NimbleGen System LLC (“NimbleGen”), a corporation organized and existing under the laws of Wisconsin.

AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT MADE BY AND AMONG NIMBLEGEN SYSTEMS, INC., a Delaware corporation, and certain of its direct and indirect subsidiaries, as “BORROWER” AND GENERAL ELECTRIC CAPITAL CORPORATION, a Delaware corporation as...
Loan and Security Agreement • March 16th, 2007 • Nimblegen Systems Inc

THIS AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT (as it may be amended, restated, supplemented or otherwise modified from time to time, together with all attachments, exhibits, schedules, riders and addenda, all of which are incorporated herein by this reference and made a part hereof, this “Agreement”), dated as of December 29, 2006, by and among NIMBLEGEN SYSTEMS, INC., a Delaware corporation (“NimbleGen”) and NIMBLEGEN SYSTEMS OF ICELAND, LLC, a Delaware limited liability company (“NimbleGen Iceland”; and together with NimbleGen, individually and collectively, “Borrower”), and GENERAL ELECTRIC CAPITAL CORPORATION, a Delaware corporation (together with its successors and assigns, collectively, “Lender”).

Contract
Licence Agreement • March 16th, 2007 • Nimblegen Systems Inc • England and Wales

NOTE: The information designated by a bracketed asterisk [*] has been omitted pursuant to a request for confidential treatment and has been filed separately with the Securities and Exchange Commission.

AMENDMENT TO LOAN DOCUMENTS
Loan Documents • March 16th, 2007 • Nimblegen Systems Inc • New York

THIS AMENDMENT TO LOAN DOCUMENTS (this “Amendment”) is made as of this 26th day of January, 2007, by and among NIMBLEGEN SYSTEMS, INC., a Delaware corporation (“NimbleGen”), and NIMBLEGEN SYSTEMS OF ICELAND, LLC, a Delaware limited liability company (“NimbleGen Iceland”; and together with NimbleGen, individually and collectively, “Borrower”), and GENERAL ELECTRIC CAPITAL CORPORATION, a Delaware corporation (together with its successors and assigns, collectively, “Lender”).

NIMBLEGEN SYSTEMS INC. SUBORDINATED CONVERTIBLE NOTE AND WARRANT PURCHASE AGREEMENT MAY 21, 2004
Purchase Common Stock • March 16th, 2007 • Nimblegen Systems Inc • Wisconsin

This SUBORDINATED CONVERTIBLE NOTE AND WARRANT PURCHASE AGREEMENT (the “Agreement”) is made and entered into as of May 21, 2004, by and among NIMBLEGEN SYSTEMS INC., a Delaware corporation (the “Company”), and those purchasers (individually, a “Purchaser” and collectively, the “Purchasers”) whose signatures appear on the signature page hereto.

COMMERCIAL USE LICENSE AGREEMENT between AFFYMETRIX, INC. and NIMBLEGEN SYSTEMS INC. dated September 26, 2006 CONFIDENTIAL
Commercial Use License Agreement • March 16th, 2007 • Nimblegen Systems Inc • Delaware

This Commercial Use License Agreement (the “Agreement”), effective as of September 26, 2006 (the “Effective Date”), is between Affymetrix, Inc., a Delaware corporation with offices located at 3420 Central Expressway, Santa Clara, California 95051, hereinafter referred to as “Affymetrix,” and NimbleGen Systems Inc., a Delaware corporation with offices located at One Science Court, Madison, Wisconsin 53711, hereinafter referred to as “NimbleGen.”

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