0001193125-07-061689 Sample Contracts

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • March 22nd, 2007 • Targacept Inc • Pharmaceutical preparations • Connecticut

THIS AGREEMENT (the “Agreement”) by and between YALE UNIVERSITY, a corporation organized and existing under and by virtue of a charter granted by the general assembly of the Colony and State of Connecticut and located in New Haven, Connecticut (“YALE”), and Targacept, Inc., a corporation organized and existing under the laws of the State of Delaware with principal offices located in Winston-Salem, North Carolina (“LICENSEE”), is effective as of the date of final signature below (“EFFECTIVE DATE”).

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NORTH CAROLINA ) ) THIRD LEASE AMENDMENT FORSYTH COUNTY )
Third Lease Amendment • March 22nd, 2007 • Targacept Inc • Pharmaceutical preparations

This Third Lease Amendment (“Amendment”) is made effective as of the 1st day of January, 2007 (the “Amendment Date”), by and between Wake Forest University Health Sciences, a North Carolina non-profit corporation having its principal office in Winston-Salem, North Carolina (“Landlord”), and Targacept, Inc., a Delaware corporation having its principal office in Winston-Salem, North Carolina (“Tenant”). Unless otherwise defined herein, all of the capitalized terms of this Amendment shall have the same meanings ascribed to them in the Lease effective August 1, 2002, as amended by the First Lease Amendment effective January 1, 2005 (the “First Lease Amendment”) and the Second Lease Amendment effective March 31, 2006 (the “Second Lease Amendment”), which is hereinafter referred to as the “Lease.”

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