0001193125-07-169565 Sample Contracts

COMMON STOCK PURCHASE AGREEMENT
Common Stock Purchase Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • New York
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TERCICA, INC. SECOND AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • California

This Second Amended and Restated Investors’ Rights Agreement (the “Agreement”) is made as of July 30, 2007 by and among Tercica, Inc., a Delaware corporation (the “Company”), the holders of the Company’s Common Stock set forth on Exhibit A hereto (the “Investors”) and the Founders listed on Exhibit B hereto (the “Founders”).

Re: Amendment re Initial Indication 2 in the U.S. IGF-1 Agreement
u.s. Igf-1 Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations

Genentech, Inc. (“Genentech”) and Tercica, Inc. (“Tercica”) are parties to that certain License and Collaboration Agreement, effective as of April 15, 2002, as amended (“U.S. IGF-1 Agreement”) and that certain International License and Collaboration Agreement, effective as of July 25, 2003, as amended (“International IGF-1 Agreement”), pursuant to which Tercica licensed from Genentech certain rights to develop and commercialize IGF-1 in the United States and in all foreign countries, respectively, (such agreements, collectively, the “IGF-1 Agreements”). All capitalized terms not otherwise defined herein shall have the meanings defined in the U.S. IGF-1 Agreement.

THIRD AMENDMENT TO LEASE
Lease Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • California

THIS THIRD AMENDMENT TO LEASE (“Third Amendment”) is made effective and entered into as of July 6, 2007, by and between 2000 SIERRA POINT PARKWAY LLC, a Delaware limited liability company (“Landlord”), and TERCICA, INC., a Delaware corporation (“Tenant”).

SECOND AMENDMENT TO LEASE
Lease Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • California

THIS SECOND AMENDMENT TO LEASE (“Second Amendment”) is made effective and entered into as of January 4, 2007, by and between 2000 SIERRA POINT PARKWAY LLC, a Delaware limited liability company (“Landlord”), and TERCICA, INC., a Delaware corporation (“Tenant”).

TERCICA, INC. AMENDMENT NO. 1 TO REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • New York

THIS AMENDMENT NO. 1 (the “Amendment”) to that certain Registration Rights Agreement, dated as of October 13, 2006 (the “Rights Agreement”), is made as of July 30, 2007 (the “Effective Date”), by and among TERCICA, INC., a Delaware corporation (the “Company”), and the undersigned Holders (the “Consenting Holders”).

COMMON STOCK PURCHASE AGREEMENT
Common Stock Purchase Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • California
ADDENDUM TO THE MANUFACTURING SERVICES AGREEMENT
Manufacturing Services Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations

THIS ADDENDUM (“Addendum”) to that certain Manufacturing Services Agreement (the “Agreement”) dated December 20, 2002 by and between Cambrex Bio Science Baltimore, Inc. (“CBSB”) and Tercica Medica, Inc., as amended by that certain Amendment No. 1 dated November 10, 2006 by and between CBSB and Tercica, Inc. (f/k/a Tercica Medica, Inc.) (“Tercica”), is entered into by and between Tercica and Lonza Baltimore, Inc. (“Lonza”) and is effective as of May 11, 2007 (the “Addendum Effective Date”). Defined terms used but not otherwise defined herein shall have the meanings ascribed to them in the Agreement.

AGREEMENT
Manufacturing Agreement • August 2nd, 2007 • Tercica Inc • Pharmaceutical preparations • New York

Tercica, Inc., a company organized and existing under the laws of Delaware, USA, established and having its principal office at 2000 Sierra Point Parkway, Suite 400, Brisbane, CA 94005 USA, (“COMPANY”) on the one part; and

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