0001193125-07-182719 Sample Contracts

AMENDED AND RESTATED SUPPLY AGREEMENT
Amended And • August 14th, 2007 • Novacea Inc • Pharmaceutical preparations • New Jersey

THIS AMENDED AND RESTATED SUPPLY AGREEMENT (the “Agreement”) is entered into this 25th day of May, 2007 (the “Effective Date”) by and between PLANTEX USA, Inc., a corporation organized under the laws of the State of New Jersey with offices at 2 University Plaza, Suite 305, Hackensack, New Jersey 07601 (“PLANTEX”) and NOVACEA, Inc. (formerly known as D-Novo Therapeutics, Inc.) a corporation organized under the laws of the State of Delaware with offices at 601 Gateway Blvd., Suite 800, South San Francisco, Ca 94080 (“NOVACEA”) and hereby amends and restates that certain Supply Agreement as amended on or about January 24, 2006, March 21, 2006 and March 13, 2007 (the “Original Agreement”) entered into between the parties effective as of 27th day of December, 2001 (the “Original Effective Date”).

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AMENDED AND RESTATED LICENSE AGREEMENT
License Agreement • August 14th, 2007 • Novacea Inc • Pharmaceutical preparations • Pennsylvania

This Amended and Restated License Agreement (the “Agreement”) is made and entered into as of the 24th day of May, 2007 (the “Effective Date”), by and between the UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, a non-profit corporation, organized and existing under the laws of the Commonwealth of Pennsylvania, having its principal office at 4200 Fifth Avenue, Pittsburgh, Pennsylvania 15260 (“UNIVERSITY”) and NOVACEA, INC., a Delaware corporation having its primary place of business at 601 Gateway Boulevard, Suite 800, South San Francisco, California 94080 (“LICENSEE”).

AMENDED AND RESTATED EXCLUSIVE LICENSE AGREEMENT BETWEEN OHSU AND NOVACEA, INC.
Exclusive License Agreement • August 14th, 2007 • Novacea Inc • Pharmaceutical preparations • Oregon

This Amended and Restated Agreement (hereinafter this “Agreement”) is made and entered into as of May 25, 2007 (“Effective Date”) between the Oregon Health & Science University (hereinafter OHSU) having offices at 2525 S.W. First Avenue, Suite 120, Portland, Oregon 97201, and Novacea, Inc. (formerly known as D-Novo Therapeutics, Inc.) (hereinafter Licensee), a Delaware corporation having offices at 601 Gateway Blvd., Suite 800, South San Francisco, California 94080; and hereby amends and restates the Exclusive License Agreement between OHSU and Licensee effective June 27, 2001 (the “Original License Agreement”).

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