0001193125-07-189909 Sample Contracts

August 21, 2007 Mr. Charles R. Eyler El Dorado Hills, CA 95762 Dear Mr. Eyler:
Cougar Biotechnology, Inc. • August 27th, 2007 • Pharmaceutical preparations • Dorado

This letter (the “Letter Amendment”) shall confirm our understanding as to the amendment of certain terms of that employment letter agreement dated August 5, 2004 (the “Agreement”) between Cougar Biotechnology, Inc. (“Cougar”) and you relating to your employment as Vice President of Finance of Cougar.

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