0001193125-08-144123 Sample Contracts

—Courtesy Translation Only— Supplemental Agreement
Supplemental Agreement • June 30th, 2008 • GPC Biotech Ag • Pharmaceutical preparations

GPC Biotech AG, Martinsried, Germany and Dr. Bernd R. Seizinger entered into a Service Agreement, dated March 1, 2007, and a Service Agreement Amendment, dated December 14 (together the “Service Agreement). The Service Agreement is supplemented by the parties; §3 paragraphs 5 and 6 are being replaced and §12 paragraph 5 is being inserted:

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SERVICE AGREEMENT AMENDMENT
Service Agreement • June 30th, 2008 • GPC Biotech Ag • Pharmaceutical preparations

In accordance with the resolution adopted by the Supervisory Board of GPC Biotech AG on December 14, 2007, the Supervisory Board desires that Dr. Bernd Seizinger Fraunhoferstrasse 20, 82152 Martinsried/Planegg (hereinafter the “Chief Executive Officer”) spent the majority of his time in the US. In accordance §3 Nr. 1 2nd sentence of the Service Agreement between GPC Biotech AG, Fraunhoferstrasse 20, 82152 Martinsried/Planegg (hereinafter the “Company”) and the Chief Executive Officer (hereinafter, the “Service Agreement”), said agreement is hereby amended as follows:

Courtesy Translation from German SERVICE AGREEMENT between GPC Biotech Aktiengesellschaft Fraunhoferstr. 20 82152 Martinsried/Planegg (hereinafter “Company”) and Dr. Torsten Hombeck c/o GPC Biotech AG Fraunhoferstr. 20 82152 Martinsried/Planegg...
Service Agreement • June 30th, 2008 • GPC Biotech Ag • Pharmaceutical preparations

payable in 12 equal monthly installments by electronic fund transfer to accounts to be specified by the Management Board Member. The salary shall be reviewed annually in the third quarter. The economic performance of the Company, the personal performance of the Management Board Member as well as any increase in the cost of living are to be taken into reasonable consideration in this regard.

LICENSE AGREEMENT
License Agreement • June 30th, 2008 • GPC Biotech Ag • Pharmaceutical preparations • New York

This License Agreement (the “Agreement”) is made and entered into effective as of June 25th, 2007 (the “Effective Date”) by and between GPC Biotech AG, a German corporation, having its place of business at Fraunhoferstrasse 20, 82152 Martinsried/Munich, Germany (“GPC Biotech”); and Yakult Honsha Co. Ltd., a Japanese company, having a place of business at 1-19 Higashi Shimbashi 1-chome, Minato-ku, Tokyo, Japan (“Yakult”). GPC Biotech and Yakult are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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