0001193125-09-053916 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • March 13th, 2009 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

This Employment Agreement (“Agreement”) is entered into as of the day of , by and between (“Executive”) and Orexigen Therapeutics, Inc. (the “Company”) and is contingent on final approval by the Company’s Board of Directors.

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NALTREXONE HYDROCHLORIDE SUPPLY AGREEMENT
Naltrexone Hydrochloride Supply Agreement • March 13th, 2009 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • California

This Naltrexone Hydrochloride Supply Agreement (this “Agreement”) is made as of this day of January 5, 2009 (the “Effective Date”) by and among OREXIGEN THERAPEUTICS, INC. (“OREXIGEN”), a Delaware corporation located at 3344 N. Torrey Pines Court, Suite 200, La Jolla, CA 92037, and CILAG GMBH INTERNATIONAL (“CILAG”), a corporation of Switzerland located at Landis+Gyr-Strasse 1, 6300 Zug, Switzerland.

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