0001193125-09-180485 Sample Contracts

Form of Aplindore CVR Agreement CONTINGENT VALUE RIGHTS AGREEMENT
Contingent Value Rights Agreement • August 24th, 2009 • Ligand Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

THIS CONTINGENT VALUE RIGHTS AGREEMENT, dated as of [ — ], 2009 (this “Agreement”, is entered into by and among Ligand Pharmaceuticals Incorporated, a Delaware corporation (“Buyer”), Neurogen Corporation, a Delaware corporation (“Target”), and [ — ], a [ — ], as Rights Agent (the “Rights Agent”) and as initial Aplindore CVR Registrar (as defined herein).

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Form of H3 CVR Agreement CONTINGENT VALUE RIGHTS AGREEMENT
Contingent Value Rights Agreement • August 24th, 2009 • Ligand Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

THIS CONTINGENT VALUE RIGHTS AGREEMENT, dated as of [ — ], 2009 (this “Agreement”, is entered into by and among Ligand Pharmaceuticals Incorporated, a Delaware corporation (“Buyer”), Neurogen Corporation, a Delaware corporation (“Target”), and [ — ], a [ — ], as Rights Agent (the “Rights Agent”) and as initial H3 CVR Registrar (as defined herein).

VOTING AGREEMENT
Voting Agreement • August 24th, 2009 • Ligand Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

This VOTING AGREEMENT (this “Agreement”), is made and entered into on and as of August , 2009, by and between Ligand Pharmaceuticals Incorporated, a Delaware corporation (“Parent”), and the undersigned stockholder (“Stockholder”) of Neurogen Corporation, a Delaware corporation (the “Company”).

Form of Real Estate CVR Agreement CONTINGENT VALUE RIGHTS AGREEMENT
Value Rights Agreement • August 24th, 2009 • Ligand Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

THIS CONTINGENT VALUE RIGHTS AGREEMENT, dated as of [ — ], 2009 (this “Agreement”, is entered into by and among Ligand Pharmaceuticals Incorporated, a Delaware corporation (“Buyer”), Neurogen Corporation, a Delaware corporation (“Target”), and [ — ], a [ — ], as Rights Agent (the “Rights Agent”) and as initial Real Estate CVR Registrar (as defined herein).

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