0001193125-09-231224 Sample Contracts

METABASIS THERAPEUTICS, INC. AMENDMENT TO OFFER LETTER AND SEVERANCE AGREEMENT
Offer Letter and Severance Agreement • November 12th, 2009 • Metabasis Therapeutics Inc • Pharmaceutical preparations • California

This Amendment to Offer Letter and Severance Agreement (the “Amendment”) is hereby entered into by and between Tran Nguyen (“Employee”) and Metabasis Therapeutics, Inc., a Delaware corporation (the “Company”) (each a “Party” and together, the “Parties”) effective as of October 12, 2009 (the “Effective Date”), and amends the Offer Letter dated February 17, 2009 between the Parties (the “Offer Letter”) and the Amended and Restated Severance Agreement between the Parties dated March 20, 2009 (the “Severance Agreement”).

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