0001193125-10-051371 Sample Contracts

FOURTH AMENDMENT TO LEASE RE TERMINATION OF LEASE AS TO 3931 SORRENTO
Lease • March 9th, 2010 • Acadia Pharmaceuticals Inc • Pharmaceutical preparations
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AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • March 9th, 2010 • Acadia Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT (the “Amendment”) is entered into as of October 5, 2009 (the “Amendment Effective Date”) by and between ACADIA PHARMACEUTICALS INC., a Delaware corporation (“ACADIA”) with offices at 3911 Sorrento Valley Blvd., San Diego, CA 92121, and BIOVAIL LABORATORIES INTERNATIONAL SRL, a Barbados society with restricted liability (“BLS”), having its registered office at Welches, Christ Church, Barbados WI, BB17154.

VOLUME SUBMITTER DEFINED CONTRIBUTION PLAN (PROFIT SHARING/401(K) PLAN) A FIDELITY VOLUME SUBMITTER PLAN Adoption Agreement No. 001 For use With Fidelity Basic Plan Document No. 14
Defined Contribution Plan • March 9th, 2010 • Acadia Pharmaceuticals Inc • Pharmaceutical preparations

Note: If the vesting schedule is amended and a Participant’s vested interest calculated using the amended vesting schedule is less in any year than the Participant’s vested interest calculated under the Plan’s vesting schedule in effect immediately before the amendment, the amended vesting schedule shall apply only to Employees hired on or after the effective date of the amendment. Please select paragraph (e) below and complete Section (b) of the Vesting Schedule Addendum to the Adoption Agreement describing the vesting schedule in effect for Employees hired before the effective date of the amendment.

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