AGREEMENT AND PLAN OF MERGER BY AND AMONG ASTELLAS PHARMA INC., ASTELLAS US HOLDING, INC., RUBY ACQUISITION, INC., AND OSI PHARMACEUTICALS, INC. DATED AS OF MAY 16, 2010Merger Agreement • May 17th, 2010 • Astellas Pharma Inc. • In vitro & in vivo diagnostic substances • Delaware
AGREEMENT AND PLAN OF MERGER, dated as of May 16, 2010 (this “Agreement”), by and among Astellas Pharma Inc., a corporation formed under the laws of Japan (“Parent”), Astellas US Holding, Inc., a Delaware corporation and a wholly-owned subsidiary of the Parent, Ruby Acquisition, Inc., a Delaware corporation and a direct wholly-owned subsidiary of Holding and an indirect wholly-owned subsidiary of Parent (“Merger Sub”), and OSI Pharmaceuticals, Inc. a Delaware corporation (the “Company”).
