0001193125-10-133081 Sample Contracts

AMENDMENT TO OFFER LETTER
Offer Letter • June 4th, 2010 • Curis Inc • Biological products, (no disgnostic substances) • Delaware

This Amendment (the “Amendment”), effective as of June 3, 2010 (the “Effective Date”), to the offer letter dated March 21, 2008 (the “Offer Letter”) by and between Curis, Inc., a Delaware corporation (the “Company”), and Dr. Mitchell Keegan (the “Executive”).

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CURIS, INC. Restricted Stock Agreement
Restricted Stock Agreement • June 4th, 2010 • Curis Inc • Biological products, (no disgnostic substances) • Delaware

Curis, Inc. (the “Company”) has selected you to receive the restricted stock award described above, which is subject to the provisions of the Company’s 2010 Stock Incentive Plan (the “Plan”) and the terms and conditions contained in this Restricted Stock Agreement. Please confirm your acceptance of this restricted stock award and of the terms and conditions of this Agreement by signing a copy of this Agreement where indicated below.

CURIS, INC. Nonstatutory Stock Option Agreement Granted Under 2010 Stock Incentive Plan
Nonstatutory Stock Option Agreement • June 4th, 2010 • Curis Inc • Biological products, (no disgnostic substances)

This Nonstatutory Stock Option Agreement certifies that, pursuant to the Curis, Inc. 2010 Stock Incentive Plan (the “Plan”), the Board has granted an option to purchase shares of Common Stock of Curis, Inc., as stated below. Capitalized terms used herein and not defined shall have the meanings ascribed to such terms in the Plan.

CURIS, INC. Incentive Stock Option Agreement Granted Under 2010 Stock Incentive Plan
Incentive Stock Option Agreement • June 4th, 2010 • Curis Inc • Biological products, (no disgnostic substances)

This Incentive Stock Option Agreement certifies that, pursuant to the Curis, Inc. 2010 Stock Incentive Plan (the “Plan”), the Board has granted an option to purchase shares of Common Stock of Curis, Inc., as stated below. Capitalized terms used herein and not defined shall have the meanings ascribed to such terms in the Plan.

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