0001193125-10-179473 Sample Contracts

Re: Amendment to Commercial Real Estate Lease
Commercial Real Estate Lease • August 5th, 2010 • Durect Corp • Pharmaceutical preparations

Reference is made to that Commercial Real Estate Lease (the “Lease”) entered into by and between Durect Corporation, a Delaware corporation, (“LESSEE”) and EWE, Inc., an Alabama corporation dated September 21, 2004 (“LESSOR”). All capitalized terms used herein shall have the meaning ascribed to such terms in the Lease.

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* *] SUPPLY AGREEMENT
Supply Agreement • August 5th, 2010 • Durect Corp • Pharmaceutical preparations

This [* * *] Supply Agreement (“Agreement”) is effective as of June 1, 2010 (the “Effective Date”) by and between Durect Corporation, a corporation established under the laws of Delaware, and having its principal business offices at 2 Results Way, Cupertino, California 95014, United States of America (“Durect”) and Hospira, Inc, a corporation having its principal business offices at 275 N Field Drive, Lake Forest, IL 60045 (“Hospira”).

Contract
Development and License Agreement • August 5th, 2010 • Durect Corp • Pharmaceutical preparations

Confidential treatment has been sought for portions of this Agreement. The copy filed herewith omits the information subject to the confidential treatment request. Omissions are designated as * * *. A complete version of this exhibit has been filed separately with the Securities and Exchange Commission.

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