0001193125-10-180242 Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • August 6th, 2010 • Arena Pharmaceuticals Inc • Pharmaceutical preparations • New York

This SECURITIES PURCHASE AGREEMENT (this “Agreement”), dated as of August 5, 2010, is by and among Arena Pharmaceuticals, Inc. (the “Company”) and Deerfield Private Design Fund, L.P., Deerfield Private Design International, L.P., Deerfield Partners, L.P., Deerfield International Limited, Deerfield Special Situations Fund, L.P. and Deerfield Special Situations Fund International Limited (collectively the “Investors”).

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AMENDMENT TO FACILITY AGREEMENT
To Facility Agreement • August 6th, 2010 • Arena Pharmaceuticals Inc • Pharmaceutical preparations

AMENDMENT dated August 5, 2010 (this “Amendment”) to the FACILITY AGREEMENT (the “Agreement”), dated as of June 17, 2009 (the “Agreement Date”), between Arena Pharmaceuticals, Inc., a Delaware corporation (the “Borrower”), and those lenders set forth on the signature page hereof (individually, a “Lender” and together, the “Lenders” and, collectively with the Borrower, the “Parties”), pursuant to which the Lenders agreed to lend to the Borrower up to $100,000,000, subject to the terms and conditions set forth in the Agreement.

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